Leukocyte tyrosine kinase receptor · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt P29376. Use UniProt P29376 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P29376 as the stable identity anchor, then attach disease evidence before program review.
Leukocyte tyrosine kinase receptor
Review this target as Leukocyte tyrosine kinase receptor, mapped to UniProt P29376. Sequence length is 864 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Leukocyte tyrosine kinase receptor as ChEMBL target CHEMBL5627, mapped to UniProt P29376. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Leukocyte tyrosine kinase receptor |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P29376 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Leukocyte tyrosine kinase receptor |
| UniProt Accession | P29376 |
| Component Type | Protein |
| Sequence Length | 864 aa |
Leukocyte tyrosine kinase receptor
Review this target as Leukocyte tyrosine kinase receptor, mapped to UniProt P29376. Sequence length is 864 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3301622 | 9.46 | IC50 | 0.35 | Approved |
| CHEMBL4546504 | 9.25 | IC50 | 0.567 | Preclinical |
| CHEMBL509032 | 9.02 | Kd | 0.95 | Preclinical |
| CHEMBL464552 | 8.96 | Kd | 1.1 | Preclinical |
| CHEMBL1983268 | 8.8 | Ki | 1.585 | Approved |
| CHEMBL461876 | 8.8 | Ki | 1.585 | Preclinical |
| CHEMBL601719 | 8.74 | IC50 | 1.8 | Approved |
| CHEMBL3128069 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL1164265 | 8.7 | Ki | 1.995 | Preclinical |
| CHEMBL2172308 | 8.6 | Kd | 2.5 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 199 | 59 | 6.4 |
| assay format | 32 | 4 | 8.4 |
| cell-based format | 11 | 4 | 7.9 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 192 | 6.1 |