1-deoxy-D-xylulose 5-phosphate reductoisomerase · SINGLE PROTEIN · Mycobacterium tuberculosis
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As of 2026-09-14Protein identity stays anchored to UniProt P9WNS1. Use UniProt P9WNS1 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P9WNS1 as the stable identity anchor, then attach disease evidence before program review.
1-deoxy-D-xylulose 5-phosphate reductoisomerase
Review this target as 1-deoxy-D-xylulose 5-phosphate reductoisomerase, mapped to UniProt P9WNS1. Sequence length is 413 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats 1-deoxy-D-xylulose 5-phosphate reductoisomerase as ChEMBL target CHEMBL5630, mapped to UniProt P9WNS1. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | 1-deoxy-D-xylulose 5-phosphate reductoisomerase |
| Target Type | SINGLE PROTEIN |
| Organism | Mycobacterium tuberculosis |
| UniProt | P9WNS1 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | 1-deoxy-D-xylulose 5-phosphate reductoisomerase |
| UniProt Accession | P9WNS1 |
| Component Type | Protein |
| Sequence Length | 413 aa |
1-deoxy-D-xylulose 5-phosphate reductoisomerase
Review this target as 1-deoxy-D-xylulose 5-phosphate reductoisomerase, mapped to UniProt P9WNS1. Sequence length is 413 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2431008 | 8.04 | IC50 | 9.2 | Preclinical |
| CHEMBL203125 | 7.4 | Kd | 40.0 | Clinical |
| CHEMBL2407192 | 7.4 | Kd | 40.0 | Preclinical |
| CHEMBL2431007 | 7.38 | IC50 | 42.0 | Preclinical |
| CHEMBL203125 | 7.1 | IC50 | 80.0 | Clinical |
| CHEMBL2164257 | 7.1 | IC50 | 80.0 | Preclinical |
| CHEMBL2407187 | 7.05 | Kd | 90.0 | Preclinical |
| CHEMBL2407189 | 7.05 | Kd | 90.0 | Preclinical |
| CHEMBL4474216 | 7.0 | IC50 | 100.0 | Preclinical |
| CHEMBL2431010 | 6.96 | IC50 | 110.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 14 | 60 | 5.9 |
| cell-based format | 5 | 7 | 5.8 |
| assay format | 4 | 29 | 5.5 |