Eukaryotic translation initiation factor 4E · SINGLE PROTEIN · Oryctolagus cuniculus
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt P29338. Use UniProt P29338 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P29338 as the stable identity anchor, then attach disease evidence before program review.
Eukaryotic translation initiation factor 4E
Review this target as Eukaryotic translation initiation factor 4E, mapped to UniProt P29338. Sequence length is 217 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Eukaryotic translation initiation factor 4E as ChEMBL target CHEMBL5636, mapped to UniProt P29338. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Eukaryotic translation initiation factor 4E |
| Target Type | SINGLE PROTEIN |
| Organism | Oryctolagus cuniculus |
| UniProt | P29338 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Eukaryotic translation initiation factor 4E |
| UniProt Accession | P29338 |
| Component Type | Protein |
| Sequence Length | 217 aa |
Eukaryotic translation initiation factor 4E
Review this target as Eukaryotic translation initiation factor 4E, mapped to UniProt P29338. Sequence length is 217 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4640985 | 6.55 | IC50 | 280.0 | Preclinical |
| CHEMBL3351004 | 6.25 | IC50 | 560.0 | Preclinical |
| CHEMBL3604542 | 6.25 | IC50 | 560.0 | Preclinical |
| CHEMBL2046906 | 6.16 | IC50 | 700.0 | Preclinical |
| CHEMBL3351002 | 5.96 | IC50 | 1100.0 | Preclinical |
| CHEMBL4299205 | 5.92 | IC50 | 1190.0 | Preclinical |
| CHEMBL3604540 | 5.91 | IC50 | 1240.0 | Preclinical |
| CHEMBL3604543 | 5.89 | IC50 | 1300.0 | Preclinical |
| CHEMBL4298680 | 5.89 | IC50 | 1300.0 | Preclinical |
| CHEMBL4640855 | 5.85 | IC50 | 1400.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 12 | 34 | 5.4 |
| cell-based format | 1 | 0 | — |