Serine/threonine-protein kinase 35 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt Q8TDR2. Use UniProt Q8TDR2 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q8TDR2 as the stable identity anchor, then attach disease evidence before program review.
Serine/threonine-protein kinase 35
Review this target as Serine/threonine-protein kinase 35, mapped to UniProt Q8TDR2. Sequence length is 534 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Serine/threonine-protein kinase 35 as ChEMBL target CHEMBL5651, mapped to UniProt Q8TDR2. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Serine/threonine-protein kinase 35 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q8TDR2 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Serine/threonine-protein kinase 35 |
| UniProt Accession | Q8TDR2 |
| Component Type | Protein |
| Sequence Length | 534 aa |
Serine/threonine-protein kinase 35
Review this target as Serine/threonine-protein kinase 35, mapped to UniProt Q8TDR2. Sequence length is 534 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL288441 | 8.7 | Kd | 2.0 | Approved |
| CHEMBL491473 | 8.27 | Kd | 5.4 | Clinical |
| CHEMBL1721885 | 8.09 | Kd | 8.2 | Clinical |
| CHEMBL574738 | 7.8 | Kd | 16.0 | Preclinical |
| CHEMBL377300 | 7.58 | Kd | 26.0 | Clinical |
| CHEMBL24828 | 7.25 | Kd | 56.0 | Approved |
| CHEMBL388978 | 6.85 | Kd | 140.0 | Preclinical |
| CHEMBL1230609 | 6.64 | Kd | 230.0 | Clinical |
| CHEMBL509032 | 6.58 | Kd | 260.0 | Preclinical |
| CHEMBL386051 | 6.44 | Kd | 360.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 71 | 23 | 6.5 |
| assay format | 16 | 1 | 5.9 |
| subcellular format | 4 | 0 | — |
| cell-based format | 1 | 0 | — |