Use UniProt Q9GRG7 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL5672 Target Snapshot
Glucose-6-phosphate 1-dehydrogenase · SINGLE PROTEIN · Trypanosoma brucei
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As of 2026-09-14Protein identity stays anchored to UniProt Q9GRG7. Use UniProt Q9GRG7 as the stable identity anchor, then attach disease evidence before program review.
Glucose-6-phosphate 1-dehydrogenase
Review this target as Glucose-6-phosphate 1-dehydrogenase, mapped to UniProt Q9GRG7. Sequence length is 521 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Glucose-6-phosphate 1-dehydrogenase as ChEMBL target CHEMBL5672, mapped to UniProt Q9GRG7. Disease framing currently uses the Open Targets-ready proxy contract.
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Open Review-ready CardBasic Information
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| Preferred Name | Glucose-6-phosphate 1-dehydrogenase |
| Target Type | SINGLE PROTEIN |
| Organism | Trypanosoma brucei |
| UniProt | Q9GRG7 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Glucose-6-phosphate 1-dehydrogenase |
| UniProt Accession | Q9GRG7 |
| Component Type | Protein |
| Sequence Length | 521 aa |
Glucose-6-phosphate 1-dehydrogenase
How to read this target
Review this target as Glucose-6-phosphate 1-dehydrogenase, mapped to UniProt Q9GRG7. Sequence length is 521 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL272195 | 6.34 | Ki | 460.0 | Preclinical |
| CHEMBL90593 | 5.96 | Ki | 1100.0 | Approved |
pChEMBL Value Distribution
Assay Landscape
Binding — 2 assays, 2 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 2 | 2 | 6.1 |