Serine/threonine-protein kinase TAO3 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt Q9H2K8. Use UniProt Q9H2K8 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9H2K8 as the stable identity anchor, then attach disease evidence before program review.
Serine/threonine-protein kinase TAO3
Review this target as Serine/threonine-protein kinase TAO3, mapped to UniProt Q9H2K8. Sequence length is 898 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Serine/threonine-protein kinase TAO3 as ChEMBL target CHEMBL5701, mapped to UniProt Q9H2K8. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Serine/threonine-protein kinase TAO3 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9H2K8 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Serine/threonine-protein kinase TAO3 |
| UniProt Accession | Q9H2K8 |
| Component Type | Protein |
| Sequence Length | 898 aa |
Serine/threonine-protein kinase TAO3
Review this target as Serine/threonine-protein kinase TAO3, mapped to UniProt Q9H2K8. Sequence length is 898 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL388978 | 9.66 | Kd | 0.22 | Preclinical |
| CHEMBL388978 | 8.96 | IC50 | 1.09 | Preclinical |
| CHEMBL574738 | 8.24 | Kd | 5.8 | Preclinical |
| CHEMBL3688339 | 7.68 | Kd | 21.0 | Preclinical |
| CHEMBL450786 | 7.37 | Kd | 43.0 | Preclinical |
| CHEMBL509032 | 7.36 | Kd | 44.0 | Preclinical |
| CHEMBL2334586 | 7.35 | IC50 | 45.0 | Preclinical |
| CHEMBL477772 | 7.35 | Kd | 45.0 | Approved |
| CHEMBL3717287 | 7.3 | IC50 | 50.0 | Preclinical |
| CHEMBL3717391 | 7.3 | IC50 | 50.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 156 | 45 | 6.5 |
| assay format | 20 | 51 | 7.1 |
| cell-based format | 18 | 0 | — |
| subcellular format | 10 | 20 | 5.4 |