NS3 · SINGLE PROTEIN · West Nile virus
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt K4FQI5. Use UniProt K4FQI5 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt K4FQI5 as the stable identity anchor, then attach disease evidence before program review.
NS3
Review this target as NS3, mapped to UniProt K4FQI5. Sequence length is 133 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats NS3 as ChEMBL target CHEMBL5705861, mapped to UniProt K4FQI5. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether NS3 is the right protein anchor across sources, using UniProt K4FQI5 as the stable mapping.
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| Preferred Name | NS3 |
| Target Type | SINGLE PROTEIN |
| Organism | West Nile virus |
| UniProt | K4FQI5 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | NS3 |
| UniProt Accession | K4FQI5 |
| Component Type | Protein |
| Sequence Length | 133 aa |
NS3
Review this target as NS3, mapped to UniProt K4FQI5. Sequence length is 133 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3919119 | 7.19 | IC50 | 65.0 | Preclinical |
| CHEMBL5605366 | 6.94 | IC50 | 115.0 | Preclinical |
| CHEMBL5598576 | 6.89 | IC50 | 129.0 | Preclinical |
| CHEMBL5604080 | 6.88 | IC50 | 131.0 | Preclinical |
| CHEMBL5599838 | 6.82 | IC50 | 152.0 | Preclinical |
| CHEMBL5604456 | 6.81 | IC50 | 154.0 | Preclinical |
| CHEMBL5598743 | 6.73 | IC50 | 186.0 | Preclinical |
| CHEMBL5605559 | 6.73 | IC50 | 185.0 | Preclinical |
| CHEMBL5598575 | 6.71 | IC50 | 193.0 | Preclinical |
| CHEMBL5605022 | 6.62 | IC50 | 242.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 3 | 292 | 5.2 |