NS3 protease · SINGLE PROTEIN · dengue virus type 1
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As of 2026-09-14Protein identity stays anchored to UniProt A0A0K0TQ28. Use UniProt A0A0K0TQ28 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt A0A0K0TQ28 as the stable identity anchor, then attach disease evidence before program review.
NS3 protease
Review this target as NS3 protease, mapped to UniProt A0A0K0TQ28. Sequence length is 186 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats NS3 protease as ChEMBL target CHEMBL5705862, mapped to UniProt A0A0K0TQ28. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether NS3 protease is the right protein anchor across sources, using UniProt A0A0K0TQ28 as the stable mapping.
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| Preferred Name | NS3 protease |
| Target Type | SINGLE PROTEIN |
| Organism | dengue virus type 1 |
| UniProt | A0A0K0TQ28 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | NS3 protease |
| UniProt Accession | A0A0K0TQ28 |
| Component Type | Protein |
| Sequence Length | 186 aa |
NS3 protease
Review this target as NS3 protease, mapped to UniProt A0A0K0TQ28. Sequence length is 186 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3919119 | 6.51 | IC50 | 310.0 | Preclinical |
| CHEMBL3740727 | 6.06 | IC50 | 865.0 | Preclinical |
| CHEMBL5598684 | 5.91 | IC50 | 1242.0 | Preclinical |
| CHEMBL5604470 | 5.78 | IC50 | 1680.0 | Preclinical |
| CHEMBL5599838 | 5.69 | IC50 | 2056.0 | Preclinical |
| CHEMBL5605103 | 5.66 | IC50 | 2189.0 | Preclinical |
| CHEMBL5604216 | 5.62 | IC50 | 2412.0 | Preclinical |
| CHEMBL5604989 | 5.57 | IC50 | 2687.0 | Preclinical |
| CHEMBL5606201 | 5.57 | IC50 | 2690.0 | Preclinical |
| CHEMBL5605664 | 5.55 | IC50 | 2796.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 65 | 5.0 |