NS3 protease · SINGLE PROTEIN · dengue virus type 3
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As of 2026-09-14Protein identity stays anchored to UniProt A0A0B5JFF1. Use UniProt A0A0B5JFF1 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt A0A0B5JFF1 as the stable identity anchor, then attach disease evidence before program review.
Nonstructural protein NS3
Review this target as NS3 protease, mapped to UniProt A0A0B5JFF1. ChEMBL maps the protein component as Nonstructural protein NS3. Sequence length is 74 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats NS3 protease as ChEMBL target CHEMBL5705863, mapped to UniProt A0A0B5JFF1. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | NS3 protease |
| Target Type | SINGLE PROTEIN |
| Organism | dengue virus type 3 |
| UniProt | A0A0B5JFF1 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Nonstructural protein NS3 |
| UniProt Accession | A0A0B5JFF1 |
| Component Type | Protein |
| Sequence Length | 74 aa |
Nonstructural protein NS3
Review this target as NS3 protease, mapped to UniProt A0A0B5JFF1. ChEMBL maps the protein component as Nonstructural protein NS3. Sequence length is 74 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3919119 | 6.11 | IC50 | 784.0 | Preclinical |
| CHEMBL3740727 | 5.83 | IC50 | 1495.0 | Preclinical |
| CHEMBL5598684 | 5.83 | IC50 | 1475.0 | Preclinical |
| CHEMBL5604470 | 5.77 | IC50 | 1704.0 | Preclinical |
| CHEMBL5599838 | 5.66 | IC50 | 2207.0 | Preclinical |
| CHEMBL5605103 | 5.66 | IC50 | 2196.0 | Preclinical |
| CHEMBL5604216 | 5.64 | IC50 | 2307.0 | Preclinical |
| CHEMBL5604989 | 5.56 | IC50 | 2730.0 | Preclinical |
| CHEMBL5605664 | 5.53 | IC50 | 2955.0 | Preclinical |
| CHEMBL5605274 | 5.46 | IC50 | 3444.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 82 | 4.9 |