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Target Snapshot

CHEMBL5724622 Target Snapshot

Malignant T-cell-amplified sequence 1 · SINGLE PROTEIN · Homo sapiens

82Compounds
7Assays
0Approved Drugs
83.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-15

Protein identity stays anchored to UniProt Q9ULC4. Use UniProt Q9ULC4 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt Q9ULC4 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-15
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Malignant T-cell-amplified sequence 1 as ChEMBL target CHEMBL5724622, mapped to UniProt Q9ULC4. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Malignant T-cell-amplified sequence 1
SINGLE PROTEIN · Homo sapiens
As of 2026-09-15
ChEMBL target ID
CHEMBL5724622
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-15
www.ebi.ac.uk
UniProt accession
Q9ULC4
Malignant T-cell-amplified sequence 1
UniProt accession via ChEMBL component mapping As of 2026-09-15
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-15
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

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UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Malignant T-cell-amplified sequence 1 is the right protein anchor across sources, using UniProt Q9ULC4 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelMalignant T-cell-amplified sequence 1
UniProt AccessionQ9ULC4
Component TypeProtein
Sequence Length181 aa

Malignant T-cell-amplified sequence 1

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Malignant T-cell-amplified sequence 1, mapped to UniProt Q9ULC4. Sequence length is 181 aa.

Mapped IDQ9ULC4
Review nameMalignant T-cell-amplified sequence 1
OrganismHomo sapiens
Clinical Profile

Clinical Phase Distribution

1
Phase II
Assay Mix

Activity Type Distribution

IC5083.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL5981118 7.26 IC50 54.5 Preclinical
CHEMBL5874865 7.0 IC50 100.0 Preclinical
CHEMBL6018589 7.0 IC50 100.0 Preclinical
CHEMBL5898165 6.69 IC50 204.0 Preclinical
CHEMBL5904074 6.69 IC50 204.0 Preclinical
CHEMBL5883085 6.52 IC50 303.0 Preclinical
CHEMBL6031816 6.52 IC50 302.0 Preclinical
CHEMBL6052282 6.52 IC50 303.0 Preclinical
CHEMBL5918774 6.4 IC50 400.0 Preclinical
CHEMBL5764687 6.39 IC50 404.0 Preclinical
Distribution

pChEMBL Value Distribution

4
5.0
0
5.5
4
6.0
5
6.5
3
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

7
Total Assays
82
Tested Compounds
1
Assay Types
Binding — 7 assays, 82 compounds
BAO Format Assays Compounds Avg pChEMBL
single protein format 6 1 5.0
assay format 1 81 4.8

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine