H/ACA ribonucleoprotein complex subunit DKC1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt O60832. Use UniProt O60832 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O60832 as the stable identity anchor, then attach disease evidence before program review.
H/ACA ribonucleoprotein complex subunit DKC1
Review this target as H/ACA ribonucleoprotein complex subunit DKC1, mapped to UniProt O60832. Sequence length is 514 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats H/ACA ribonucleoprotein complex subunit DKC1 as ChEMBL target CHEMBL5724912, mapped to UniProt O60832. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether H/ACA ribonucleoprotein complex subunit DKC1 is the right protein anchor across sources, using UniProt O60832 as the stable mapping.
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| Preferred Name | H/ACA ribonucleoprotein complex subunit DKC1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | O60832 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | H/ACA ribonucleoprotein complex subunit DKC1 |
| UniProt Accession | O60832 |
| Component Type | Protein |
| Sequence Length | 514 aa |
H/ACA ribonucleoprotein complex subunit DKC1
Review this target as H/ACA ribonucleoprotein complex subunit DKC1, mapped to UniProt O60832. Sequence length is 514 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1232461 | 8.22 | Kd | 6.0 | Clinical |
| CHEMBL1232461 | 8.0 | IC50 | 10.0 | Clinical |
| CHEMBL3752910 | 5.5 | Kd | 3138.76 | Preclinical |
| CHEMBL5653589 | 5.22 | Kd | 5989.49 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 8 | 3 | 6.7 |