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Target Snapshot

CHEMBL5725138 Target Snapshot

Arginine/serine-rich protein PNISR · SINGLE PROTEIN · Homo sapiens

1Compounds
7Assays
0Approved Drugs
2.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Protein identity stays anchored to UniProt Q8TF01. Use UniProt Q8TF01 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt Q8TF01 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Arginine/serine-rich protein PNISR as ChEMBL target CHEMBL5725138, mapped to UniProt Q8TF01. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Arginine/serine-rich protein PNISR
SINGLE PROTEIN · Homo sapiens
As of 2026-09-13
ChEMBL target ID
CHEMBL5725138
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
UniProt accession
Q8TF01
Arginine/serine-rich protein PNISR
UniProt accession via ChEMBL component mapping As of 2026-09-13
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Arginine/serine-rich protein PNISR is the right protein anchor across sources, using UniProt Q8TF01 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelArginine/serine-rich protein PNISR
UniProt AccessionQ8TF01
Component TypeProtein
Sequence Length805 aa

Arginine/serine-rich protein PNISR

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Arginine/serine-rich protein PNISR, mapped to UniProt Q8TF01. Sequence length is 805 aa.

Mapped IDQ8TF01
Review nameArginine/serine-rich protein PNISR
OrganismHomo sapiens
Clinical Profile

Clinical Phase Distribution

1
Phase II
Assay Mix

Activity Type Distribution

IC501.0
KD1.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL1232461 8.1 Kd 8.0 Clinical
Distribution

pChEMBL Value Distribution

0
5.0
0
5.5
0
6.0
0
6.5
0
7.0
0
7.5
1
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

7
Total Assays
1
Tested Compounds
1
Assay Types
Binding — 7 assays, 1 compounds
BAO Format Assays Compounds Avg pChEMBL
single protein format 7 1 8.1

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine