Pancreatic alpha-amylase · SINGLE PROTEIN · Sus scrofa
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As of 2026-09-14Protein identity stays anchored to UniProt P00690. Use UniProt P00690 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P00690 as the stable identity anchor, then attach disease evidence before program review.
Pancreatic alpha-amylase
Review this target as Pancreatic alpha-amylase, mapped to UniProt P00690. Sequence length is 511 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Pancreatic alpha-amylase as ChEMBL target CHEMBL5730, mapped to UniProt P00690. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Pancreatic alpha-amylase is the right protein anchor across sources, using UniProt P00690 as the stable mapping.
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| Preferred Name | Pancreatic alpha-amylase |
| Target Type | SINGLE PROTEIN |
| Organism | Sus scrofa |
| UniProt | P00690 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Pancreatic alpha-amylase |
| UniProt Accession | P00690 |
| Component Type | Protein |
| Sequence Length | 511 aa |
Pancreatic alpha-amylase
Review this target as Pancreatic alpha-amylase, mapped to UniProt P00690. Sequence length is 511 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4861741 | 6.42 | IC50 | 380.0 | Preclinical |
| CHEMBL5276306 | 6.23 | IC50 | 590.0 | Preclinical |
| CHEMBL404271 | 5.87 | IC50 | 1353.0 | Approved |
| CHEMBL4277658 | 5.8 | IC50 | 1571.0 | Preclinical |
| CHEMBL4864128 | 5.78 | IC50 | 1660.0 | Preclinical |
| CHEMBL4284909 | 5.68 | IC50 | 2064.0 | Preclinical |
| CHEMBL4294256 | 5.67 | IC50 | 2118.0 | Preclinical |
| CHEMBL4292777 | 5.63 | IC50 | 2348.0 | Preclinical |
| CHEMBL4290115 | 5.57 | IC50 | 2670.0 | Preclinical |
| CHEMBL4286367 | 5.56 | IC50 | 2751.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 50 | 63 | 5.0 |
| tissue-based format | 1 | 1 | 6.2 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 3 | 0 | — |