Atypical kinase COQ8B, mitochondrial · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q96D53. Use UniProt Q96D53 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q96D53 as the stable identity anchor, then attach disease evidence before program review.
Atypical kinase COQ8B, mitochondrial
Review this target as Atypical kinase COQ8B, mitochondrial, mapped to UniProt Q96D53. Sequence length is 544 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Atypical kinase COQ8B, mitochondrial as ChEMBL target CHEMBL5753, mapped to UniProt Q96D53. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Atypical kinase COQ8B, mitochondrial |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q96D53 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Atypical kinase COQ8B, mitochondrial |
| UniProt Accession | Q96D53 |
| Component Type | Protein |
| Sequence Length | 544 aa |
Atypical kinase COQ8B, mitochondrial
Review this target as Atypical kinase COQ8B, mitochondrial, mapped to UniProt Q96D53. Sequence length is 544 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL386051 | 7.57 | Kd | 27.0 | Preclinical |
| CHEMBL475251 | 7.19 | Kd | 64.0 | Clinical |
| CHEMBL509032 | 7.04 | Kd | 92.0 | Preclinical |
| CHEMBL249097 | 6.89 | Kd | 129.0 | Preclinical |
| CHEMBL1287853 | 6.52 | Kd | 300.0 | Approved |
| CHEMBL601719 | 5.96 | Kd | 1100.0 | Approved |
| CHEMBL230011 | 5.85 | Kd | 1400.0 | Clinical |
| CHEMBL24828 | 5.77 | Kd | 1700.0 | Approved |
| CHEMBL553 | 5.6 | Kd | 2500.0 | Approved |
| CHEMBL296468 | 5.54 | Kd | 2900.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 53 | 16 | 5.9 |
| assay format | 15 | 0 | — |
| subcellular format | 8 | 0 | — |
| cell-based format | 1 | 0 | — |