Use UniProt O32393 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL5755 Target Snapshot
Adenylate cyclase · SINGLE PROTEIN · Arthrospira platensis
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As of 2026-09-14Protein identity stays anchored to UniProt O32393. Use UniProt O32393 as the stable identity anchor, then attach disease evidence before program review.
histidine kinase
Review this target as Adenylate cyclase, mapped to UniProt O32393. ChEMBL maps the protein component as histidine kinase. Sequence length is 1202 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Adenylate cyclase as ChEMBL target CHEMBL5755, mapped to UniProt O32393. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Adenylate cyclase is the right protein anchor across sources, using UniProt O32393 as the stable mapping.
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Open Review-ready CardBasic Information
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| Preferred Name | Adenylate cyclase |
| Target Type | SINGLE PROTEIN |
| Organism | Arthrospira platensis |
| UniProt | O32393 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | histidine kinase |
| UniProt Accession | O32393 |
| Component Type | Protein |
| Sequence Length | 1202 aa |
histidine kinase
How to read this target
Review this target as Adenylate cyclase, mapped to UniProt O32393. ChEMBL maps the protein component as histidine kinase. Sequence length is 1202 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL401844 | 5.3 | IC50 | 5000.0 | Preclinical |
| CHEMBL387152 | 4.82 | IC50 | 15000.0 | Preclinical |
| CHEMBL442 | 4.16 | IC50 | 70000.0 | Approved |
| CHEMBL469203 | 4.0 | IC50 | 100000.0 | Preclinical |
| CHEMBL481854 | 4.0 | IC50 | 100000.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 1 assays, 6 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 1 | 6 | 4.5 |