Use UniProt P96878 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL5767 Target Snapshot
PROBABLE TRANSMEMBRANE CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE) · SINGLE PROTEIN · Mycobacterium tuberculosis
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As of 2026-09-14Protein identity stays anchored to UniProt P96878. Use UniProt P96878 as the stable identity anchor, then attach disease evidence before program review.
carbonic anhydrase
Review this target as PROBABLE TRANSMEMBRANE CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE), mapped to UniProt P96878. ChEMBL maps the protein component as carbonic anhydrase. Sequence length is 764 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats PROBABLE TRANSMEMBRANE CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE) as ChEMBL target CHEMBL5767, mapped to UniProt P96878. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether PROBABLE TRANSMEMBRANE CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE) is the right protein anchor across sources, using UniProt P96878 as the stable mapping.
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| Preferred Name | PROBABLE TRANSMEMBRANE CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE) |
| Target Type | SINGLE PROTEIN |
| Organism | Mycobacterium tuberculosis |
| UniProt | P96878 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | carbonic anhydrase |
| UniProt Accession | P96878 |
| Component Type | Protein |
| Sequence Length | 764 aa |
carbonic anhydrase
How to read this target
Review this target as PROBABLE TRANSMEMBRANE CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE), mapped to UniProt P96878. ChEMBL maps the protein component as carbonic anhydrase. Sequence length is 764 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL501294 | 9.03 | Ki | 0.93 | Preclinical |
| CHEMBL1614844 | 8.19 | Ki | 6.5 | Preclinical |
| CHEMBL316779 | 8.19 | Ki | 6.4 | Preclinical |
| CHEMBL512633 | 8.14 | Ki | 7.2 | Preclinical |
| CHEMBL20 | 7.92 | Ki | 12.0 | Approved |
| CHEMBL77517 | 7.82 | Ki | 15.0 | Clinical |
| CHEMBL6633 | 7.48 | Ki | 33.0 | Preclinical |
| CHEMBL467897 | 7.42 | Ki | 38.0 | Preclinical |
| CHEMBL6724 | 7.4 | Ki | 40.0 | Preclinical |
| CHEMBL1615281 | 7.28 | Ki | 53.0 | Preclinical |
pChEMBL Value Distribution
Approved Drugs
Assay Landscape
Binding — 7 assays, 101 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 7 | 101 | 6.2 |