Prolyl endopeptidase FAP · SINGLE PROTEIN · Mus musculus
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As of 2026-09-13Protein identity stays anchored to UniProt P97321. Use UniProt P97321 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P97321 as the stable identity anchor, then attach disease evidence before program review.
Prolyl endopeptidase FAP
Review this target as Prolyl endopeptidase FAP, mapped to UniProt P97321. Sequence length is 761 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Prolyl endopeptidase FAP as ChEMBL target CHEMBL5769, mapped to UniProt P97321. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Prolyl endopeptidase FAP is the right protein anchor across sources, using UniProt P97321 as the stable mapping.
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| Preferred Name | Prolyl endopeptidase FAP |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | P97321 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Prolyl endopeptidase FAP |
| UniProt Accession | P97321 |
| Component Type | Protein |
| Sequence Length | 761 aa |
Prolyl endopeptidase FAP
Review this target as Prolyl endopeptidase FAP, mapped to UniProt P97321. Sequence length is 761 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2385281 | 8.52 | Ki | 3.0 | Preclinical |
| CHEMBL3233842 | 8.49 | IC50 | 3.2 | Preclinical |
| CHEMBL3233840 | 8.48 | IC50 | 3.3 | Preclinical |
| CHEMBL3233847 | 8.43 | IC50 | 3.7 | Preclinical |
| CHEMBL2385300 | 8.39 | Ki | 4.1 | Preclinical |
| CHEMBL3233835 | 8.37 | IC50 | 4.3 | Preclinical |
| CHEMBL2385273 | 8.21 | IC50 | 6.2 | Preclinical |
| CHEMBL3233834 | 8.16 | IC50 | 6.9 | Preclinical |
| CHEMBL3900683 | 8.16 | IC50 | 6.9 | Preclinical |
| CHEMBL2385272 | 8.15 | IC50 | 7.1 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 9 | 62 | 6.0 |
| single protein format | 9 | 71 | 6.5 |