Sodium/nucleoside cotransporter 2 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt O43868. Use UniProt O43868 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O43868 as the stable identity anchor, then attach disease evidence before program review.
Sodium/nucleoside cotransporter 2
Review this target as Sodium/nucleoside cotransporter 2, mapped to UniProt O43868. Sequence length is 658 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Sodium/nucleoside cotransporter 2 as ChEMBL target CHEMBL5780, mapped to UniProt O43868. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Sodium/nucleoside cotransporter 2 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | O43868 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Sodium/nucleoside cotransporter 2 |
| UniProt Accession | O43868 |
| Component Type | Protein |
| Sequence Length | 658 aa |
Sodium/nucleoside cotransporter 2
Review this target as Sodium/nucleoside cotransporter 2, mapped to UniProt O43868. Sequence length is 658 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3808747 | 7.21 | IC50 | 62.0 | Preclinical |
| CHEMBL3427690 | 6.19 | IC50 | 640.0 | Preclinical |
| CHEMBL3809613 | 6.03 | IC50 | 940.0 | Preclinical |
| CHEMBL3809974 | 6.0 | IC50 | 1000.0 | Preclinical |
| CHEMBL3809075 | 5.96 | IC50 | 1100.0 | Preclinical |
| CHEMBL3809514 | 5.96 | IC50 | 1100.0 | Preclinical |
| CHEMBL3808410 | 5.92 | IC50 | 1200.0 | Preclinical |
| CHEMBL3809978 | 5.89 | IC50 | 1300.0 | Preclinical |
| CHEMBL3809204 | 5.89 | IC50 | 1300.0 | Preclinical |
| CHEMBL3809948 | 5.82 | IC50 | 1500.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 8 | 36 | 5.4 |
| single protein format | 7 | 5 | 5.1 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 3 | 4.9 |
| cell-based format | 1 | 0 | — |