Leukotriene A-4 hydrolase · SINGLE PROTEIN · Cavia porcellus
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As of 2026-09-14Protein identity stays anchored to UniProt P19602. Use UniProt P19602 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P19602 as the stable identity anchor, then attach disease evidence before program review.
Leukotriene A-4 hydrolase
Review this target as Leukotriene A-4 hydrolase, mapped to UniProt P19602. Sequence length is 611 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Leukotriene A-4 hydrolase as ChEMBL target CHEMBL5786, mapped to UniProt P19602. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Leukotriene A-4 hydrolase is the right protein anchor across sources, using UniProt P19602 as the stable mapping.
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| Preferred Name | Leukotriene A-4 hydrolase |
| Target Type | SINGLE PROTEIN |
| Organism | Cavia porcellus |
| UniProt | P19602 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Leukotriene A-4 hydrolase |
| UniProt Accession | P19602 |
| Component Type | Protein |
| Sequence Length | 611 aa |
Leukotriene A-4 hydrolase
Review this target as Leukotriene A-4 hydrolase, mapped to UniProt P19602. Sequence length is 611 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL459959 | 7.82 | IC50 | 15.0 | Preclinical |
| CHEMBL513671 | 7.82 | IC50 | 15.14 | Preclinical |
| CHEMBL461022 | 7.62 | IC50 | 23.99 | Preclinical |
| CHEMBL463320 | 7.62 | IC50 | 24.0 | Preclinical |
| CHEMBL500409 | 7.51 | IC50 | 31.0 | Preclinical |
| CHEMBL502817 | 7.47 | IC50 | 34.0 | Preclinical |
| CHEMBL511849 | 7.34 | IC50 | 45.71 | Preclinical |
| CHEMBL449792 | 7.28 | IC50 | 52.0 | Preclinical |
| CHEMBL456045 | 7.26 | IC50 | 55.0 | Preclinical |
| CHEMBL458238 | 7.26 | IC50 | 55.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 6 | 48 | 6.4 |