Ephrin type-B receptor 6 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt O15197. Use UniProt O15197 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O15197 as the stable identity anchor, then attach disease evidence before program review.
Ephrin type-B receptor 6
Review this target as Ephrin type-B receptor 6, mapped to UniProt O15197. Sequence length is 1021 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Ephrin type-B receptor 6 as ChEMBL target CHEMBL5836, mapped to UniProt O15197. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Ephrin type-B receptor 6 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | O15197 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Ephrin type-B receptor 6 |
| UniProt Accession | O15197 |
| Component Type | Protein |
| Sequence Length | 1021 aa |
Ephrin type-B receptor 6
Review this target as Ephrin type-B receptor 6, mapped to UniProt O15197. Sequence length is 1021 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5416410 | 10.41 | Kd | 0.039 | Approved |
| CHEMBL400402 | 9.22 | Kd | 0.6 | Preclinical |
| CHEMBL1230609 | 8.89 | Kd | 1.3 | Clinical |
| CHEMBL386051 | 8.7 | Kd | 2.0 | Preclinical |
| CHEMBL1908396 | 8.3 | Kd | 5.0 | Preclinical |
| CHEMBL601719 | 8.22 | Kd | 6.0 | Approved |
| CHEMBL3907479 | 8.15 | Kd | 7.0 | Clinical |
| CHEMBL5415503 | 8.0 | Kd | 10.0 | Preclinical |
| CHEMBL495727 | 7.92 | Kd | 12.0 | Clinical |
| CHEMBL3545085 | 7.58 | Kd | 26.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 58 | 48 | 6.5 |
| assay format | 21 | 6 | 5.7 |
| cell-based format | 5 | 3 | 6.1 |
| subcellular format | 1 | 22 | 6.7 |