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Target Snapshot

CHEMBL5848 Target Snapshot

Oligo-1,6-glucosidase IMA1 · SINGLE PROTEIN · Saccharomyces cerevisiae S288c

175Compounds
27Assays
1Approved Drugs
160.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Protein identity stays anchored to UniProt P53051. Use UniProt P53051 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt P53051 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Oligo-1,6-glucosidase IMA1 as ChEMBL target CHEMBL5848, mapped to UniProt P53051. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Oligo-1,6-glucosidase IMA1
SINGLE PROTEIN · Saccharomyces cerevisiae S288c
As of 2026-09-14
ChEMBL target ID
CHEMBL5848
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
P53051
Oligo-1,6-glucosidase IMA1
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Oligo-1,6-glucosidase IMA1 is the right protein anchor across sources, using UniProt P53051 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelOligo-1,6-glucosidase IMA1
UniProt AccessionP53051
Component TypeProtein
Sequence Length589 aa

Oligo-1,6-glucosidase IMA1

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Oligo-1,6-glucosidase IMA1, mapped to UniProt P53051. Sequence length is 589 aa.

Mapped IDP53051
Review nameOligo-1,6-glucosidase IMA1
OrganismSaccharomyces cerevisiae S288c
Clinical Profile

Clinical Phase Distribution

1
Approved
Assay Mix

Activity Type Distribution

IC50150.0
KI10.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL2414818 5.64 IC50 2300.0 Preclinical
CHEMBL3397482 5.32 IC50 4800.0 Preclinical
CHEMBL1765390 5.31 Ki 4860.0 Preclinical
CHEMBL2414819 5.25 IC50 5600.0 Preclinical
CHEMBL3397478 4.92 IC50 12100.0 Preclinical
CHEMBL3891396 4.83 Ki 14780.0 Preclinical
CHEMBL3891396 4.82 IC50 15160.0 Preclinical
CHEMBL3397479 4.8 IC50 15700.0 Preclinical
CHEMBL3397481 4.8 IC50 16000.0 Preclinical
CHEMBL3901489 4.77 IC50 17030.0 Preclinical
Distribution

pChEMBL Value Distribution

3
5.0
1
5.5
0
6.0
0
6.5
0
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

27
Total Assays
122
Tested Compounds
1
Assay Types
Binding — 27 assays, 122 compounds
BAO Format Assays Compounds Avg pChEMBL
single protein format 27 122 4.5

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine