Hematopoietic prostaglandin D synthase · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt O60760. Use UniProt O60760 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O60760 as the stable identity anchor, then attach disease evidence before program review.
Hematopoietic prostaglandin D synthase
Review this target as Hematopoietic prostaglandin D synthase, mapped to UniProt O60760. Sequence length is 199 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Hematopoietic prostaglandin D synthase as ChEMBL target CHEMBL5879, mapped to UniProt O60760. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Hematopoietic prostaglandin D synthase |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | O60760 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Hematopoietic prostaglandin D synthase |
| UniProt Accession | O60760 |
| Component Type | Protein |
| Sequence Length | 199 aa |
Hematopoietic prostaglandin D synthase
Review this target as Hematopoietic prostaglandin D synthase, mapped to UniProt O60760. Sequence length is 199 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4238290 | 9.85 | Kd | 0.14 | Preclinical |
| CHEMBL2035650 | 9.7 | IC50 | 0.2 | Preclinical |
| CHEMBL5285108 | 9.62 | Kd | 0.24 | Preclinical |
| CHEMBL4238186 | 9.43 | Kd | 0.37 | Preclinical |
| CHEMBL4473072 | 9.3 | Kd | 0.5 | Preclinical |
| CHEMBL2035651 | 8.63 | IC50 | 2.34 | Preclinical |
| CHEMBL5272869 | 8.62 | IC50 | 2.4 | Preclinical |
| CHEMBL4247050 | 8.52 | IC50 | 3.0 | Preclinical |
| CHEMBL5289520 | 8.51 | IC50 | 3.1 | Preclinical |
| CHEMBL5289730 | 8.42 | IC50 | 3.8 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 30 | 193 | 6.7 |
| assay format | 16 | 138 | 6.1 |
| cell-based format | 12 | 70 | 7.5 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 1 | 0 | — |