Lysine-specific demethylase 4A · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt O75164. Use UniProt O75164 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O75164 as the stable identity anchor, then attach disease evidence before program review.
Lysine-specific demethylase 4A
Review this target as Lysine-specific demethylase 4A, mapped to UniProt O75164. Sequence length is 1064 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Lysine-specific demethylase 4A as ChEMBL target CHEMBL5896, mapped to UniProt O75164. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Lysine-specific demethylase 4A is the right protein anchor across sources, using UniProt O75164 as the stable mapping.
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| Preferred Name | Lysine-specific demethylase 4A |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | O75164 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Lysine-specific demethylase 4A |
| UniProt Accession | O75164 |
| Component Type | Protein |
| Sequence Length | 1064 aa |
Lysine-specific demethylase 4A
Review this target as Lysine-specific demethylase 4A, mapped to UniProt O75164. Sequence length is 1064 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4438830 | 8.7 | Ki | 2.0 | Preclinical |
| CHEMBL4204694 | 8.59 | Kd | 2.6 | Preclinical |
| CHEMBL3774537 | 8.52 | Ki | 3.0 | Preclinical |
| CHEMBL4567766 | 8.52 | Ki | 3.0 | Preclinical |
| CHEMBL4205285 | 8.51 | Kd | 3.1 | Preclinical |
| CHEMBL4205183 | 8.43 | Kd | 3.7 | Preclinical |
| CHEMBL4447515 | 8.4 | Ki | 4.0 | Preclinical |
| CHEMBL4449500 | 8.4 | Ki | 4.0 | Preclinical |
| CHEMBL4585876 | 8.4 | Ki | 4.0 | Preclinical |
| CHEMBL4573390 | 8.3 | Ki | 5.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 84 | 166 | 6.0 |
| assay format | 32 | 161 | 6.2 |
| cell-based format | 25 | 33 | 5.2 |
| biochemical format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 2 | 1 | 7.4 |
| cell-based format | 1 | 0 | — |