ATP-binding cassette sub-family C member 3 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt O15438. Use UniProt O15438 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O15438 as the stable identity anchor, then attach disease evidence before program review.
ATP-binding cassette sub-family C member 3
Review this target as ATP-binding cassette sub-family C member 3, mapped to UniProt O15438. Sequence length is 1527 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats ATP-binding cassette sub-family C member 3 as ChEMBL target CHEMBL5918, mapped to UniProt O15438. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether ATP-binding cassette sub-family C member 3 is the right protein anchor across sources, using UniProt O15438 as the stable mapping.
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| Preferred Name | ATP-binding cassette sub-family C member 3 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | O15438 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | ATP-binding cassette sub-family C member 3 |
| UniProt Accession | O15438 |
| Component Type | Protein |
| Sequence Length | 1527 aa |
ATP-binding cassette sub-family C member 3
Review this target as ATP-binding cassette sub-family C member 3, mapped to UniProt O15438. Sequence length is 1527 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL160 | 6.2 | IC50 | 631.5 | Approved |
| CHEMBL589973 | 5.96 | IC50 | 1100.0 | Preclinical |
| CHEMBL1200692 | 5.7 | IC50 | 2000.0 | Approved |
| CHEMBL308954 | 5.29 | IC50 | 5100.0 | Approved |
| CHEMBL1481 | 5.19 | IC50 | 6390.0 | Approved |
| CHEMBL813 | 5.18 | IC50 | 6650.0 | Approved |
| CHEMBL15177 | 5.03 | IC50 | 9300.0 | Preclinical |
| CHEMBL77305 | 4.99 | IC50 | 10200.0 | Clinical |
| CHEMBL163 | 4.96 | IC50 | 11100.0 | Approved |
| CHEMBL393220 | 4.85 | IC50 | 14200.0 | Approved |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 16 | 1 | 5.3 |
| single protein format | 4 | 1 | 6.2 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 11 | 45 | 4.5 |
| single protein format | 3 | 3 | 4.5 |
| assay format | 2 | 0 | — |