Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P22413. Use UniProt P22413 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P22413 as the stable identity anchor, then attach disease evidence before program review.
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1
Review this target as Ectonucleotide pyrophosphatase/phosphodiesterase family member 1, mapped to UniProt P22413. Sequence length is 925 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 as ChEMBL target CHEMBL5925, mapped to UniProt P22413. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P22413 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 |
| UniProt Accession | P22413 |
| Component Type | Protein |
| Sequence Length | 925 aa |
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1
Review this target as Ectonucleotide pyrophosphatase/phosphodiesterase family member 1, mapped to UniProt P22413. Sequence length is 925 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5566114 | 10.05 | IC50 | 0.09 | Preclinical |
| CHEMBL5556000 | 9.8 | IC50 | 0.16 | Preclinical |
| CHEMBL5826130 | 9.66 | IC50 | 0.22 | Preclinical |
| CHEMBL5560511 | 9.52 | IC50 | 0.3 | Preclinical |
| CHEMBL5561670 | 9.32 | IC50 | 0.48 | Preclinical |
| CHEMBL5915707 | 9.3 | IC50 | 0.5 | Preclinical |
| CHEMBL5555976 | 9.28 | IC50 | 0.52 | Preclinical |
| CHEMBL5566818 | 9.25 | IC50 | 0.56 | Preclinical |
| CHEMBL5558246 | 9.18 | IC50 | 0.66 | Preclinical |
| CHEMBL5558533 | 9.14 | IC50 | 0.72 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 67 | 132 | 6.2 |
| single protein format | 66 | 229 | 6.3 |
| assay format | 4 | 42 | 5.7 |
| cell membrane format | 4 | 8 | 5.6 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 11 | 0 | — |
| cell-based format | 2 | 0 | — |