Use UniProt P22513 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL5926 Target Snapshot
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal · SINGLE PROTEIN · Trypanosoma cruzi
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As of 2026-09-14Protein identity stays anchored to UniProt P22513. Use UniProt P22513 as the stable identity anchor, then attach disease evidence before program review.
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal
Review this target as Glyceraldehyde-3-phosphate dehydrogenase, glycosomal, mapped to UniProt P22513. Sequence length is 359 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Glyceraldehyde-3-phosphate dehydrogenase, glycosomal as ChEMBL target CHEMBL5926, mapped to UniProt P22513. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Glyceraldehyde-3-phosphate dehydrogenase, glycosomal is the right protein anchor across sources, using UniProt P22513 as the stable mapping.
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Open Review-ready CardBasic Information
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| Preferred Name | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal |
| Target Type | SINGLE PROTEIN |
| Organism | Trypanosoma cruzi |
| UniProt | P22513 |
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UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal |
| UniProt Accession | P22513 |
| Component Type | Protein |
| Sequence Length | 359 aa |
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal
How to read this target
Review this target as Glyceraldehyde-3-phosphate dehydrogenase, glycosomal, mapped to UniProt P22513. Sequence length is 359 aa.
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL552521 | 7.0 | IC50 | 100.0 | Preclinical |
| CHEMBL455368 | 5.7 | Ki | 2000.0 | Preclinical |
| CHEMBL451726 | 5.4 | Ki | 4000.0 | Preclinical |
| CHEMBL366942 | 5.3 | IC50 | 5000.0 | Preclinical |
| CHEMBL464924 | 4.92 | IC50 | 12000.0 | Preclinical |
| CHEMBL2408381 | 4.8 | Ki | 15980.0 | Preclinical |
| CHEMBL2408382 | 4.77 | Ki | 17100.0 | Preclinical |
| CHEMBL67599 | 4.75 | IC50 | 17800.0 | Preclinical |
| CHEMBL2408383 | 4.73 | Ki | 18670.0 | Preclinical |
| CHEMBL455368 | 4.55 | IC50 | 28000.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 13 assays, 30 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 7 | 21 | 4.9 |
| single protein format | 6 | 9 | 4.5 |