NAD-dependent protein deacetylase HST2 · SINGLE PROTEIN · Saccharomyces cerevisiae S288c
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As of 2026-09-14Protein identity stays anchored to UniProt P53686. Use UniProt P53686 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P53686 as the stable identity anchor, then attach disease evidence before program review.
NAD-dependent protein deacetylase HST2
Review this target as NAD-dependent protein deacetylase HST2, mapped to UniProt P53686. Sequence length is 357 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats NAD-dependent protein deacetylase HST2 as ChEMBL target CHEMBL5933, mapped to UniProt P53686. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | NAD-dependent protein deacetylase HST2 |
| Target Type | SINGLE PROTEIN |
| Organism | Saccharomyces cerevisiae S288c |
| UniProt | P53686 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | NAD-dependent protein deacetylase HST2 |
| UniProt Accession | P53686 |
| Component Type | Protein |
| Sequence Length | 357 aa |
NAD-dependent protein deacetylase HST2
Review this target as NAD-dependent protein deacetylase HST2, mapped to UniProt P53686. Sequence length is 357 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL595128 | 5.92 | Ki | 1200.0 | Preclinical |
| CHEMBL446446 | 5.89 | IC50 | 1300.0 | Preclinical |
| CHEMBL594863 | 5.6 | Ki | 2500.0 | Preclinical |
| CHEMBL1162220 | 5.48 | Kd | 3300.0 | Preclinical |
| CHEMBL1162221 | 5.48 | Kd | 3300.0 | Preclinical |
| CHEMBL446124 | 5.48 | Kd | 3300.0 | Preclinical |
| CHEMBL500219 | 5.48 | Kd | 3300.0 | Preclinical |
| CHEMBL500768 | 5.48 | Kd | 3300.0 | Preclinical |
| CHEMBL501380 | 5.48 | Kd | 3300.0 | Preclinical |
| CHEMBL525757 | 5.48 | Kd | 3300.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 11 | 22 | 5.1 |