Ephrin type-B receptor 2 · SINGLE PROTEIN · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt P54763. Use UniProt P54763 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P54763 as the stable identity anchor, then attach disease evidence before program review.
Ephrin type-B receptor 2
Review this target as Ephrin type-B receptor 2, mapped to UniProt P54763. Sequence length is 986 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Ephrin type-B receptor 2 as ChEMBL target CHEMBL5961, mapped to UniProt P54763. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Ephrin type-B receptor 2 |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | P54763 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Ephrin type-B receptor 2 |
| UniProt Accession | P54763 |
| Component Type | Protein |
| Sequence Length | 986 aa |
Ephrin type-B receptor 2
Review this target as Ephrin type-B receptor 2, mapped to UniProt P54763. Sequence length is 986 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2037224 | 5.77 | IC50 | 1700.0 | Preclinical |
| CHEMBL2037220 | 5.64 | IC50 | 2300.0 | Preclinical |
| CHEMBL2037208 | 5.62 | IC50 | 2400.0 | Preclinical |
| CHEMBL2037209 | 5.35 | IC50 | 4500.0 | Preclinical |
| CHEMBL2037226 | 5.24 | IC50 | 5800.0 | Preclinical |
| CHEMBL4761556 | 4.85 | IC50 | 14000.0 | Preclinical |
| CHEMBL448652 | 4.82 | IC50 | 15000.0 | Preclinical |
| CHEMBL3735992 | 4.8 | IC50 | 16000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 3 | 3 | 4.8 |
| cell-based format | 1 | 5 | 5.5 |