Use UniProt P84077 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL5985 Target Snapshot
ADP-ribosylation factor 1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P84077. Use UniProt P84077 as the stable identity anchor, then attach disease evidence before program review.
ADP-ribosylation factor 1
Review this target as ADP-ribosylation factor 1, mapped to UniProt P84077. Sequence length is 181 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats ADP-ribosylation factor 1 as ChEMBL target CHEMBL5985, mapped to UniProt P84077. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether ADP-ribosylation factor 1 is the right protein anchor across sources, using UniProt P84077 as the stable mapping.
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Open Review-ready CardBasic Information
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| Preferred Name | ADP-ribosylation factor 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P84077 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | ADP-ribosylation factor 1 |
| UniProt Accession | P84077 |
| Component Type | Protein |
| Sequence Length | 181 aa |
ADP-ribosylation factor 1
How to read this target
Review this target as ADP-ribosylation factor 1, mapped to UniProt P84077. Sequence length is 181 aa.
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL259181 | 6.21 | Kd | 620.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 4 assays, 1 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 2 | 0 | — |
| cell-based format | 1 | 1 | 6.2 |
| subcellular format | 1 | 0 | — |