Bile salt export pump · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt O95342. Use UniProt O95342 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O95342 as the stable identity anchor, then attach disease evidence before program review.
Bile salt export pump
Review this target as Bile salt export pump, mapped to UniProt O95342. Sequence length is 1321 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Bile salt export pump as ChEMBL target CHEMBL6020, mapped to UniProt O95342. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Bile salt export pump |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | O95342 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Bile salt export pump |
| UniProt Accession | O95342 |
| Component Type | Protein |
| Sequence Length | 1321 aa |
Bile salt export pump
Review this target as Bile salt export pump, mapped to UniProt O95342. Sequence length is 1321 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1651956 | 6.96 | IC50 | 110.0 | Clinical |
| CHEMBL3704745 | 6.75 | IC50 | 180.0 | Preclinical |
| CHEMBL595 | 6.58 | IC50 | 260.0 | Approved |
| CHEMBL4162778 | 6.52 | IC50 | 300.0 | Preclinical |
| CHEMBL160 | 6.4 | IC50 | 400.0 | Approved |
| CHEMBL4159416 | 5.85 | IC50 | 1400.0 | Preclinical |
| CHEMBL5182534 | 5.85 | IC50 | 1400.0 | Preclinical |
| CHEMBL2103735 | 5.83 | IC50 | 1470.0 | Approved |
| CHEMBL472 | 5.82 | IC50 | 1500.0 | Approved |
| CHEMBL223643 | 5.81 | IC50 | 1560.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 20 | 8 | 5.2 |
| cell-based format | 10 | 3 | 4.8 |
| cell membrane format | 2 | 41 | 5.0 |
| assay format | 1 | 3 | 6.0 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 17 | 169 | 4.8 |
| assay format | 7 | 301 | 4.7 |
| single protein format | 5 | 6 | 4.8 |
| tissue-based format | 2 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell membrane format | 7 | 6 | 4.8 |
| cell-based format | 5 | 16 | 4.6 |
| assay format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 2 | 3 | 4.5 |
| cell membrane format | 1 | 2 | 5.1 |