Use UniProt P0CS83 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL6021 Target Snapshot
Secreted aspartic protease 2 · SINGLE PROTEIN · Candida albicans
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As of 2026-09-14Protein identity stays anchored to UniProt P0CS83. Use UniProt P0CS83 as the stable identity anchor, then attach disease evidence before program review.
Secreted aspartic protease 2
Review this target as Secreted aspartic protease 2, mapped to UniProt P0CS83. Sequence length is 398 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Secreted aspartic protease 2 as ChEMBL target CHEMBL6021, mapped to UniProt P0CS83. Disease framing currently uses the Open Targets-ready proxy contract.
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Open Review-ready CardBasic Information
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| Preferred Name | Secreted aspartic protease 2 |
| Target Type | SINGLE PROTEIN |
| Organism | Candida albicans |
| UniProt | P0CS83 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Secreted aspartic protease 2 |
| UniProt Accession | P0CS83 |
| Component Type | Protein |
| Sequence Length | 398 aa |
Secreted aspartic protease 2
How to read this target
Review this target as Secreted aspartic protease 2, mapped to UniProt P0CS83. Sequence length is 398 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2206678 | 7.92 | Ki | 12.0 | Preclinical |
| CHEMBL589301 | 7.52 | IC50 | 30.0 | Preclinical |
| CHEMBL296588 | 7.05 | IC50 | 90.0 | Clinical |
| CHEMBL2206670 | 6.26 | IC50 | 550.0 | Preclinical |
| CHEMBL2206677 | 6.13 | IC50 | 740.0 | Preclinical |
| CHEMBL2206674 | 6.05 | IC50 | 900.0 | Preclinical |
| CHEMBL2206676 | 6.05 | IC50 | 890.0 | Preclinical |
| CHEMBL2206669 | 6.01 | IC50 | 980.0 | Preclinical |
| CHEMBL2206671 | 5.96 | IC50 | 1100.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 13 assays, 9 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 13 | 9 | 6.5 |