N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt O94760. Use UniProt O94760 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O94760 as the stable identity anchor, then attach disease evidence before program review.
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1
Review this target as N(G),N(G)-dimethylarginine dimethylaminohydrolase 1, mapped to UniProt O94760. Sequence length is 285 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 as ChEMBL target CHEMBL6036, mapped to UniProt O94760. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | O94760 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 |
| UniProt Accession | O94760 |
| Component Type | Protein |
| Sequence Length | 285 aa |
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1
Review this target as N(G),N(G)-dimethylarginine dimethylaminohydrolase 1, mapped to UniProt O94760. Sequence length is 285 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5423612 | 6.72 | Ki | 190.0 | Preclinical |
| CHEMBL4444007 | 6.0 | Ki | 1000.0 | Preclinical |
| CHEMBL4461206 | 5.89 | Ki | 1300.0 | Preclinical |
| CHEMBL106820 | 5.7 | Ki | 2000.0 | Preclinical |
| CHEMBL4444007 | 5.52 | IC50 | 3000.0 | Preclinical |
| CHEMBL3677847 | 5.48 | IC50 | 3300.0 | Preclinical |
| CHEMBL2070857 | 5.29 | IC50 | 5100.0 | Preclinical |
| CHEMBL3960681 | 5.26 | IC50 | 5500.0 | Preclinical |
| CHEMBL5437726 | 5.16 | Ki | 7000.0 | Preclinical |
| CHEMBL3677841 | 5.15 | IC50 | 7100.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 36 | 32 | 4.6 |
| single protein format | 34 | 44 | 4.7 |
| cell-based format | 22 | 28 | 4.9 |