Mushroom tyrosinase · PROTEIN FAMILY · Agaricus bisporus
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As of 2026-09-13Protein identity stays anchored to UniProt O42713. Use UniProt O42713 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O42713 as the stable identity anchor, then attach disease evidence before program review.
Polyphenol oxidase 2
Review this target as Mushroom tyrosinase, mapped to UniProt O42713. ChEMBL maps the protein component as Polyphenol oxidase 2. Sequence length is 556 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Mushroom tyrosinase as ChEMBL target CHEMBL6066154, mapped to UniProt O42713. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Mushroom tyrosinase is the right protein anchor across sources, using UniProt O42713 as the stable mapping.
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| Preferred Name | Mushroom tyrosinase |
| Target Type | PROTEIN FAMILY |
| Organism | Agaricus bisporus |
| UniProt | O42713 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Polyphenol oxidase 2 |
| UniProt Accession | O42713 |
| Component Type | Protein |
| Sequence Length | 556 aa |
Polyphenol oxidase 2
Review this target as Mushroom tyrosinase, mapped to UniProt O42713. ChEMBL maps the protein component as Polyphenol oxidase 2. Sequence length is 556 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5286240 | 9.52 | Ki | 0.3 | Preclinical |
| CHEMBL287556 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL5408010 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL5426437 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL5430416 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL5434603 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL5555176 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL5567981 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL5430164 | 8.52 | Ki | 3.02 | Preclinical |
| CHEMBL4128371 | 8.34 | IC50 | 4.58 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 168 | 338 | 5.8 |
| protein format | 68 | 224 | 6.0 |
| cell-based format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 6 | 1 | — |