Use UniProt O94826 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL6066210 Target Snapshot
Mitochondrial import receptor subunit TOM70 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt O94826. Use UniProt O94826 as the stable identity anchor, then attach disease evidence before program review.
Mitochondrial import receptor subunit TOM70
Review this target as Mitochondrial import receptor subunit TOM70, mapped to UniProt O94826. Sequence length is 608 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Mitochondrial import receptor subunit TOM70 as ChEMBL target CHEMBL6066210, mapped to UniProt O94826. Disease framing currently uses the Open Targets-ready proxy contract.
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Open Review-ready CardBasic Information
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| Preferred Name | Mitochondrial import receptor subunit TOM70 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | O94826 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Mitochondrial import receptor subunit TOM70 |
| UniProt Accession | O94826 |
| Component Type | Protein |
| Sequence Length | 608 aa |
Mitochondrial import receptor subunit TOM70
How to read this target
Review this target as Mitochondrial import receptor subunit TOM70, mapped to UniProt O94826. Sequence length is 608 aa.
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5653589 | 8.75 | Kd | 1.79 | Preclinical |
| CHEMBL5558181 | 5.92 | IC50 | 1200.0 | Preclinical |
| CHEMBL5561795 | 5.82 | IC50 | 1500.0 | Preclinical |
| CHEMBL5558644 | 5.3 | IC50 | 5000.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 2 assays, 4 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 3 | 5.7 |
| single protein format | 1 | 1 | 8.8 |