E3 ubiquitin-protein ligase pellino homolog 1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-15Protein identity stays anchored to UniProt Q96FA3. Use UniProt Q96FA3 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q96FA3 as the stable identity anchor, then attach disease evidence before program review.
E3 ubiquitin-protein ligase pellino homolog 1
Review this target as E3 ubiquitin-protein ligase pellino homolog 1, mapped to UniProt Q96FA3. Sequence length is 418 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats E3 ubiquitin-protein ligase pellino homolog 1 as ChEMBL target CHEMBL6066217, mapped to UniProt Q96FA3. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | E3 ubiquitin-protein ligase pellino homolog 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q96FA3 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | E3 ubiquitin-protein ligase pellino homolog 1 |
| UniProt Accession | Q96FA3 |
| Component Type | Protein |
| Sequence Length | 418 aa |
E3 ubiquitin-protein ligase pellino homolog 1
Review this target as E3 ubiquitin-protein ligase pellino homolog 1, mapped to UniProt Q96FA3. Sequence length is 418 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5560298 | 5.28 | Kd | 5200.0 | Preclinical |
| CHEMBL5542921 | 5.24 | Kd | 5800.0 | Preclinical |
| CHEMBL5566406 | 5.15 | Kd | 7100.0 | Preclinical |
| CHEMBL5412968 | 5.09 | Kd | 8200.0 | Preclinical |
| CHEMBL5562660 | 4.94 | Kd | 11400.0 | Preclinical |
| CHEMBL5559040 | 4.92 | Kd | 11900.0 | Preclinical |
| CHEMBL5410440 | 4.87 | Kd | 13620.0 | Preclinical |
| CHEMBL5440044 | 4.82 | Kd | 15300.0 | Preclinical |
| CHEMBL5432112 | 4.71 | Kd | 19720.0 | Preclinical |
| CHEMBL5435393 | 4.65 | Kd | 22600.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 40 | 4.5 |
| single protein format | 1 | 0 | — |