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CHEMBL6066234 Target Snapshot

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A · SINGLE PROTEIN · Homo sapiens

3Compounds
2Assays
0Approved Drugs
3.0Activities
Free Research Context

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Broader Open DB context

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Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Protein identity stays anchored to UniProt P46977. Use UniProt P46977 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt P46977 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Protein anchor
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A

Review this target as Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A, mapped to UniProt P46977. Sequence length is 705 aa.

Protein source · UniProt accession via ChEMBL component mapping
UniProt P46977 Protein 705 aa
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Identity Layer

Cross-source identity

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This review treats Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A as ChEMBL target CHEMBL6066234, mapped to UniProt P46977. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A
SINGLE PROTEIN · Homo sapiens
As of 2026-09-14
ChEMBL target ID
CHEMBL6066234
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
P46977
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

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UniProt Target Context
UniProt accession via ChEMBL component mapping

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
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Overview

Basic Information

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelDolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A
UniProt AccessionP46977
Component TypeProtein
Sequence Length705 aa

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A, mapped to UniProt P46977. Sequence length is 705 aa.

Mapped IDP46977
Review nameDolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A
OrganismHomo sapiens
Assay Mix

Activity Type Distribution

KD3.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL5583975 8.1 Kd 7.943 Preclinical
CHEMBL5653589 8.01 Kd 9.862 Preclinical
CHEMBL3752910 5.95 Kd 1123.85 Preclinical
Distribution

pChEMBL Value Distribution

0
5.0
1
5.5
0
6.0
0
6.5
0
7.0
0
7.5
2
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

2
Total Assays
3
Tested Compounds
1
Assay Types
Binding — 2 assays, 3 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 1 1 8.1
single protein format 1 2 7.0

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine