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Target Snapshot

CHEMBL6066518 Target Snapshot

Eukaryotic translation initiation factor 3 subunit B · SINGLE PROTEIN · Homo sapiens

2Compounds
1Assays
0Approved Drugs
2.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Protein identity stays anchored to UniProt P55884. Use UniProt P55884 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt P55884 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Eukaryotic translation initiation factor 3 subunit B as ChEMBL target CHEMBL6066518, mapped to UniProt P55884. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Eukaryotic translation initiation factor 3 subunit B
SINGLE PROTEIN · Homo sapiens
As of 2026-09-13
ChEMBL target ID
CHEMBL6066518
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
UniProt accession
P55884
Eukaryotic translation initiation factor 3 subunit B
UniProt accession via ChEMBL component mapping As of 2026-09-13
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Eukaryotic translation initiation factor 3 subunit B is the right protein anchor across sources, using UniProt P55884 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelEukaryotic translation initiation factor 3 subunit B
UniProt AccessionP55884
Component TypeProtein
Sequence Length814 aa

Eukaryotic translation initiation factor 3 subunit B

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Eukaryotic translation initiation factor 3 subunit B, mapped to UniProt P55884. Sequence length is 814 aa.

Mapped IDP55884
Review nameEukaryotic translation initiation factor 3 subunit B
OrganismHomo sapiens
Assay Mix

Activity Type Distribution

KD2.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL5653589 8.71 Kd 1.946 Preclinical
CHEMBL3752910 5.01 Kd 9871.69 Preclinical
Distribution

pChEMBL Value Distribution

1
5.0
0
5.5
0
6.0
0
6.5
0
7.0
0
7.5
0
8.0
1
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

1
Total Assays
2
Tested Compounds
1
Assay Types
Binding — 1 assays, 2 compounds
BAO Format Assays Compounds Avg pChEMBL
single protein format 1 2 6.9

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine