Use UniProt A1L390 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL6066528 Target Snapshot
Pleckstrin homology domain-containing family G member 3 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt A1L390. Use UniProt A1L390 as the stable identity anchor, then attach disease evidence before program review.
Pleckstrin homology domain-containing family G member 3
Review this target as Pleckstrin homology domain-containing family G member 3, mapped to UniProt A1L390. Sequence length is 1219 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Pleckstrin homology domain-containing family G member 3 as ChEMBL target CHEMBL6066528, mapped to UniProt A1L390. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Pleckstrin homology domain-containing family G member 3 is the right protein anchor across sources, using UniProt A1L390 as the stable mapping.
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Open Review-ready CardBasic Information
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| Preferred Name | Pleckstrin homology domain-containing family G member 3 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | A1L390 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Pleckstrin homology domain-containing family G member 3 |
| UniProt Accession | A1L390 |
| Component Type | Protein |
| Sequence Length | 1219 aa |
Pleckstrin homology domain-containing family G member 3
How to read this target
Review this target as Pleckstrin homology domain-containing family G member 3, mapped to UniProt A1L390. Sequence length is 1219 aa.
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3752910 | 9.5 | Kd | 0.315 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 1 assays, 1 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 1 | 1 | 9.5 |