Sentrin-specific protease 2/Small ubiquitin-related modifier 1 · PROTEIN COMPLEX · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P63165. Use UniProt P63165 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P63165 as the stable identity anchor, then attach disease evidence before program review.
Small ubiquitin-related modifier 1
Review this target as Sentrin-specific protease 2/Small ubiquitin-related modifier 1, mapped to UniProt P63165. ChEMBL maps the protein component as Small ubiquitin-related modifier 1. Sequence length is 101 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Sentrin-specific protease 2/Small ubiquitin-related modifier 1 as ChEMBL target CHEMBL6066556, mapped to UniProt P63165. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Sentrin-specific protease 2/Small ubiquitin-related modifier 1 is the right protein anchor across sources, using UniProt P63165 as the stable mapping.
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| Preferred Name | Sentrin-specific protease 2/Small ubiquitin-related modifier 1 |
| Target Type | PROTEIN COMPLEX |
| Organism | Homo sapiens |
| UniProt | P63165 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Small ubiquitin-related modifier 1 |
| UniProt Accession | P63165 |
| Component Type | Protein |
| Sequence Length | 101 aa |
Small ubiquitin-related modifier 1
Review this target as Sentrin-specific protease 2/Small ubiquitin-related modifier 1, mapped to UniProt P63165. ChEMBL maps the protein component as Small ubiquitin-related modifier 1. Sequence length is 101 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5276705 | 5.85 | IC50 | 1420.0 | Preclinical |
| CHEMBL2009952 | 5.8 | IC50 | 1600.0 | Preclinical |
| CHEMBL5175111 | 5.47 | IC50 | 3420.0 | Preclinical |
| CHEMBL5290662 | 5.44 | IC50 | 3620.0 | Preclinical |
| CHEMBL6030623 | 5.39 | IC50 | 4100.0 | Preclinical |
| CHEMBL5315679 | 5.29 | IC50 | 5170.0 | Preclinical |
| CHEMBL5278967 | 4.71 | IC50 | 19700.0 | Preclinical |
| CHEMBL5914455 | 4.63 | IC50 | 23600.0 | Preclinical |
| CHEMBL5315304 | 4.47 | IC50 | 34210.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| protein complex format | 1 | 9 | 5.2 |