Use UniProt P14415 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL6066561 Target Snapshot
Sodium/potassium-transporting ATPase subunit alpha-2/beta-2 · PROTEIN COMPLEX · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P14415. Use UniProt P14415 as the stable identity anchor, then attach disease evidence before program review.
Sodium/potassium-transporting ATPase subunit beta-2
Review this target as Sodium/potassium-transporting ATPase subunit alpha-2/beta-2, mapped to UniProt P14415. ChEMBL maps the protein component as Sodium/potassium-transporting ATPase subunit beta-2. Sequence length is 290 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Sodium/potassium-transporting ATPase subunit alpha-2/beta-2 as ChEMBL target CHEMBL6066561, mapped to UniProt P14415. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Sodium/potassium-transporting ATPase subunit alpha-2/beta-2 |
| Target Type | PROTEIN COMPLEX |
| Organism | Homo sapiens |
| UniProt | P14415 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Sodium/potassium-transporting ATPase subunit beta-2 |
| UniProt Accession | P14415 |
| Component Type | Protein |
| Sequence Length | 290 aa |
Sodium/potassium-transporting ATPase subunit beta-2
How to read this target
Review this target as Sodium/potassium-transporting ATPase subunit alpha-2/beta-2, mapped to UniProt P14415. ChEMBL maps the protein component as Sodium/potassium-transporting ATPase subunit beta-2. Sequence length is 290 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5876237 | 8.29 | Ki | 5.1 | Preclinical |
| CHEMBL5879229 | 8.28 | Ki | 5.3 | Preclinical |
| CHEMBL5765464 | 8.27 | Ki | 5.4 | Preclinical |
| CHEMBL5832044 | 8.17 | Ki | 6.8 | Preclinical |
| CHEMBL5748673 | 8.0 | Ki | 10.0 | Preclinical |
| CHEMBL5957388 | 7.98 | Ki | 10.5 | Preclinical |
| CHEMBL6026321 | 7.92 | Ki | 12.1 | Preclinical |
| CHEMBL6056661 | 7.89 | Ki | 13.0 | Preclinical |
| CHEMBL5851200 | 7.84 | Ki | 14.3 | Preclinical |
| CHEMBL5910596 | 7.82 | Ki | 15.3 | Preclinical |
pChEMBL Value Distribution
Approved Drugs
Assay Landscape
Binding — 1 assays, 21 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| protein complex format | 1 | 21 | 7.8 |