Baculoviral IAP repeat-containing protein 3/E3 ubiquitin-protein ligase XIAP · PROTEIN FAMILY · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P98170. Use UniProt P98170 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P98170 as the stable identity anchor, then attach disease evidence before program review.
E3 ubiquitin-protein ligase XIAP
Review this target as Baculoviral IAP repeat-containing protein 3/E3 ubiquitin-protein ligase XIAP, mapped to UniProt P98170. ChEMBL maps the protein component as E3 ubiquitin-protein ligase XIAP. Sequence length is 497 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Baculoviral IAP repeat-containing protein 3/E3 ubiquitin-protein ligase XIAP as ChEMBL target CHEMBL6066573, mapped to UniProt P98170. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Baculoviral IAP repeat-containing protein 3/E3 ubiquitin-protein ligase XIAP |
| Target Type | PROTEIN FAMILY |
| Organism | Homo sapiens |
| UniProt | P98170 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | E3 ubiquitin-protein ligase XIAP |
| UniProt Accession | P98170 |
| Component Type | Protein |
| Sequence Length | 497 aa |
E3 ubiquitin-protein ligase XIAP
Review this target as Baculoviral IAP repeat-containing protein 3/E3 ubiquitin-protein ligase XIAP, mapped to UniProt P98170. ChEMBL maps the protein component as E3 ubiquitin-protein ligase XIAP. Sequence length is 497 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5799178 | 8.72 | IC50 | 1.9 | Preclinical |
| CHEMBL5916145 | 8.72 | IC50 | 1.9 | Preclinical |
| CHEMBL5806178 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL5984721 | 8.49 | IC50 | 3.2 | Preclinical |
| CHEMBL5787995 | 8.36 | IC50 | 4.4 | Preclinical |
| CHEMBL5742728 | 8.31 | IC50 | 4.9 | Preclinical |
| CHEMBL5830887 | 8.07 | IC50 | 8.6 | Preclinical |
| CHEMBL5886173 | 8.05 | IC50 | 9.0 | Preclinical |
| CHEMBL5748523 | 8.04 | IC50 | 9.1 | Preclinical |
| CHEMBL3339219 | 8.0 | IC50 | 10.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| protein complex format | 4 | 128 | 7.3 |