Alpha amylase · PROTEIN FAMILY · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt P0DUB6. Use UniProt P0DUB6 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P0DUB6 as the stable identity anchor, then attach disease evidence before program review.
Alpha-amylase 1A
Review this target as Alpha amylase, mapped to UniProt P0DUB6. ChEMBL maps the protein component as Alpha-amylase 1A. Sequence length is 511 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Alpha amylase as ChEMBL target CHEMBL6066863, mapped to UniProt P0DUB6. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Alpha amylase is the right protein anchor across sources, using UniProt P0DUB6 as the stable mapping.
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| Preferred Name | Alpha amylase |
| Target Type | PROTEIN FAMILY |
| Organism | Homo sapiens |
| UniProt | P0DUB6 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Alpha-amylase 1A |
| UniProt Accession | P0DUB6 |
| Component Type | Protein |
| Sequence Length | 511 aa |
Alpha-amylase 1A
Review this target as Alpha amylase, mapped to UniProt P0DUB6. ChEMBL maps the protein component as Alpha-amylase 1A. Sequence length is 511 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3940413 | 8.7 | EC50 | 2.0 | Preclinical |
| CHEMBL3933500 | 8.52 | EC50 | 3.0 | Preclinical |
| CHEMBL5613512 | 8.52 | EC50 | 3.0 | Preclinical |
| CHEMBL5590766 | 7.4 | IC50 | 39.9 | Preclinical |
| CHEMBL5593047 | 7.35 | IC50 | 44.77 | Preclinical |
| CHEMBL5595096 | 7.32 | IC50 | 48.08 | Preclinical |
| CHEMBL5595111 | 7.32 | IC50 | 47.97 | Preclinical |
| CHEMBL5592906 | 7.31 | IC50 | 49.32 | Preclinical |
| CHEMBL5592459 | 7.28 | IC50 | 52.97 | Preclinical |
| CHEMBL5595454 | 7.27 | IC50 | 53.95 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 64 | 197 | 5.5 |
| protein format | 10 | 52 | 5.7 |
| tissue-based format | 4 | 5 | 5.2 |