Use UniProt O75934 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL6067001 Target Snapshot
Pre-mRNA-splicing factor SPF27 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt O75934. Use UniProt O75934 as the stable identity anchor, then attach disease evidence before program review.
Pre-mRNA-splicing factor SPF27
Review this target as Pre-mRNA-splicing factor SPF27, mapped to UniProt O75934. Sequence length is 225 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Pre-mRNA-splicing factor SPF27 as ChEMBL target CHEMBL6067001, mapped to UniProt O75934. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Pre-mRNA-splicing factor SPF27 is the right protein anchor across sources, using UniProt O75934 as the stable mapping.
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Open Review-ready CardBasic Information
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| Preferred Name | Pre-mRNA-splicing factor SPF27 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | O75934 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Pre-mRNA-splicing factor SPF27 |
| UniProt Accession | O75934 |
| Component Type | Protein |
| Sequence Length | 225 aa |
Pre-mRNA-splicing factor SPF27
How to read this target
Review this target as Pre-mRNA-splicing factor SPF27, mapped to UniProt O75934. Sequence length is 225 aa.
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3752910 | 8.72 | Kd | 1.891 | Preclinical |
| CHEMBL5653589 | 6.02 | Kd | 953.94 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 1 assays, 2 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 1 | 2 | 7.4 |