Toll-like receptor 7 · SINGLE PROTEIN · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt P58681. Use UniProt P58681 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P58681 as the stable identity anchor, then attach disease evidence before program review.
Toll-like receptor 7
Review this target as Toll-like receptor 7, mapped to UniProt P58681. Sequence length is 1050 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Toll-like receptor 7 as ChEMBL target CHEMBL6085, mapped to UniProt P58681. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Toll-like receptor 7 |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | P58681 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Toll-like receptor 7 |
| UniProt Accession | P58681 |
| Component Type | Protein |
| Sequence Length | 1050 aa |
Toll-like receptor 7
Review this target as Toll-like receptor 7, mapped to UniProt P58681. Sequence length is 1050 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5201891 | 9.52 | IC50 | 0.3 | Preclinical |
| CHEMBL5091113 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL4636498 | 8.62 | EC50 | 2.4 | Preclinical |
| CHEMBL4634860 | 8.4 | IC50 | 4.0 | Preclinical |
| CHEMBL2315158 | 8.34 | EC50 | 4.6 | Preclinical |
| CHEMBL5433689 | 8.11 | IC50 | 7.8 | Preclinical |
| CHEMBL5417170 | 8.05 | IC50 | 9.0 | Clinical |
| CHEMBL5429027 | 7.72 | EC50 | 19.0 | Preclinical |
| CHEMBL4635551 | 7.57 | EC50 | 27.0 | Preclinical |
| CHEMBL5419663 | 7.57 | EC50 | 27.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 38 | 45 | 6.6 |
| single protein format | 10 | 41 | 6.7 |
| tissue-based format | 4 | 4 | 8.1 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| organism-based format | 12 | 1 | 8.6 |