Use UniProt P61088 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL6089 Target Snapshot
Ubiquitin-conjugating enzyme E2 N · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt P61088. Use UniProt P61088 as the stable identity anchor, then attach disease evidence before program review.
Ubiquitin-conjugating enzyme E2 N
Review this target as Ubiquitin-conjugating enzyme E2 N, mapped to UniProt P61088. Sequence length is 152 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Ubiquitin-conjugating enzyme E2 N as ChEMBL target CHEMBL6089, mapped to UniProt P61088. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Ubiquitin-conjugating enzyme E2 N is the right protein anchor across sources, using UniProt P61088 as the stable mapping.
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Open Review-ready CardBasic Information
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| Preferred Name | Ubiquitin-conjugating enzyme E2 N |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P61088 |
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UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Ubiquitin-conjugating enzyme E2 N |
| UniProt Accession | P61088 |
| Component Type | Protein |
| Sequence Length | 152 aa |
Ubiquitin-conjugating enzyme E2 N
How to read this target
Review this target as Ubiquitin-conjugating enzyme E2 N, mapped to UniProt P61088. Sequence length is 152 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3192949 | 6.41 | IC50 | 386.0 | Preclinical |
| CHEMBL1521485 | 6.29 | IC50 | 509.0 | Preclinical |
| CHEMBL3192124 | 6.29 | IC50 | 507.0 | Preclinical |
| CHEMBL1509569 | 6.25 | IC50 | 561.0 | Preclinical |
| CHEMBL1558306 | 6.23 | IC50 | 594.0 | Preclinical |
| CHEMBL1326930 | 6.18 | IC50 | 664.0 | Preclinical |
| CHEMBL1381940 | 6.15 | IC50 | 709.0 | Preclinical |
| CHEMBL1418004 | 6.12 | IC50 | 763.0 | Preclinical |
| CHEMBL1462994 | 6.08 | IC50 | 829.0 | Preclinical |
| CHEMBL1226 | 6.06 | IC50 | 873.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 8 assays, 0 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 8 | 0 | — |
Functional — 2 assays, 324 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 2 | 324 | 5.1 |