Aryl hydrocarbon receptor · SINGLE PROTEIN · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt P30561. Use UniProt P30561 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P30561 as the stable identity anchor, then attach disease evidence before program review.
Aryl hydrocarbon receptor
Review this target as Aryl hydrocarbon receptor, mapped to UniProt P30561. Sequence length is 848 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Aryl hydrocarbon receptor as ChEMBL target CHEMBL6099, mapped to UniProt P30561. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Aryl hydrocarbon receptor |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | P30561 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Aryl hydrocarbon receptor |
| UniProt Accession | P30561 |
| Component Type | Protein |
| Sequence Length | 848 aa |
Aryl hydrocarbon receptor
Review this target as Aryl hydrocarbon receptor, mapped to UniProt P30561. Sequence length is 848 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL30327 | 10.52 | EC50 | 0.03 | Preclinical |
| CHEMBL5186309 | 10.24 | EC50 | 0.058 | Preclinical |
| CHEMBL1324296 | 8.52 | Kd | 3.0 | Preclinical |
| CHEMBL1324296 | 8.0 | EC50 | 10.0 | Preclinical |
| CHEMBL1324296 | 8.0 | Ki | 10.0 | Preclinical |
| CHEMBL2420083 | 7.68 | IC50 | 21.0 | Preclinical |
| CHEMBL283196 | 7.6 | IC50 | 25.0 | Preclinical |
| CHEMBL5198290 | 7.06 | Ki | 88.0 | Preclinical |
| CHEMBL446452 | 7.05 | Kd | 90.0 | Clinical |
| CHEMBL5179114 | 6.1 | Ki | 800.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 42 | 6 | 6.9 |
| assay format | 3 | 3 | 6.6 |
| subcellular format | 3 | 3 | 7.0 |
| single protein format | 1 | 1 | 8.5 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 1 | 10.5 |