Use UniProt P08047 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL6103 Target Snapshot
Transcription factor Sp1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P08047. Use UniProt P08047 as the stable identity anchor, then attach disease evidence before program review.
Transcription factor Sp1
Review this target as Transcription factor Sp1, mapped to UniProt P08047. Sequence length is 785 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Transcription factor Sp1 as ChEMBL target CHEMBL6103, mapped to UniProt P08047. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Transcription factor Sp1 is the right protein anchor across sources, using UniProt P08047 as the stable mapping.
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Open Review-ready CardBasic Information
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| Preferred Name | Transcription factor Sp1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P08047 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Transcription factor Sp1 |
| UniProt Accession | P08047 |
| Component Type | Protein |
| Sequence Length | 785 aa |
Transcription factor Sp1
How to read this target
Review this target as Transcription factor Sp1, mapped to UniProt P08047. Sequence length is 785 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2105734 | 8.1 | IC50 | 8.0 | Clinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 8 assays, 1 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 6 | 0 | — |
| assay format | 1 | 0 | — |
| cell-based format | 1 | 1 | 8.1 |
ADME — 2 assays, 0 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 2 | 0 | — |