Use UniProt Q8TCT1 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL6113 Target Snapshot
Phosphoethanolamine/phosphocholine phosphatase · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt Q8TCT1. Use UniProt Q8TCT1 as the stable identity anchor, then attach disease evidence before program review.
Phosphoethanolamine/phosphocholine phosphatase
Review this target as Phosphoethanolamine/phosphocholine phosphatase, mapped to UniProt Q8TCT1. Sequence length is 267 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Phosphoethanolamine/phosphocholine phosphatase as ChEMBL target CHEMBL6113, mapped to UniProt Q8TCT1. Disease framing currently uses the Open Targets-ready proxy contract.
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Open Review-ready CardBasic Information
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| Preferred Name | Phosphoethanolamine/phosphocholine phosphatase |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q8TCT1 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Phosphoethanolamine/phosphocholine phosphatase |
| UniProt Accession | Q8TCT1 |
| Component Type | Protein |
| Sequence Length | 267 aa |
Phosphoethanolamine/phosphocholine phosphatase
How to read this target
Review this target as Phosphoethanolamine/phosphocholine phosphatase, mapped to UniProt Q8TCT1. Sequence length is 267 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1732623 | 7.63 | IC50 | 23.3 | Preclinical |
| CHEMBL1724427 | 7.46 | IC50 | 34.8 | Preclinical |
| CHEMBL1606007 | 7.14 | IC50 | 72.5 | Preclinical |
| CHEMBL1714665 | 7.0 | IC50 | 100.0 | Preclinical |
| CHEMBL51085 | 6.96 | IC50 | 111.0 | Clinical |
| CHEMBL1570441 | 6.86 | IC50 | 139.0 | Preclinical |
| CHEMBL1725457 | 6.72 | IC50 | 192.5 | Preclinical |
| CHEMBL1717022 | 6.63 | IC50 | 233.0 | Preclinical |
| CHEMBL1727796 | 6.6 | IC50 | 252.0 | Preclinical |
| CHEMBL1705022 | 6.45 | IC50 | 359.0 | Preclinical |
pChEMBL Value Distribution
Approved Drugs
Assay Landscape
Binding — 4 assays, 66 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 4 | 66 | 5.8 |