Lysosomal protective protein · SINGLE PROTEIN · Homo sapiens
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-13Protein identity stays anchored to UniProt P10619. Use UniProt P10619 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P10619 as the stable identity anchor, then attach disease evidence before program review.
Lysosomal protective protein
Review this target as Lysosomal protective protein, mapped to UniProt P10619. Sequence length is 480 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Lysosomal protective protein as ChEMBL target CHEMBL6115, mapped to UniProt P10619. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Lysosomal protective protein is the right protein anchor across sources, using UniProt P10619 as the stable mapping.
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| Preferred Name | Lysosomal protective protein |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P10619 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Lysosomal protective protein |
| UniProt Accession | P10619 |
| Component Type | Protein |
| Sequence Length | 480 aa |
Lysosomal protective protein
Review this target as Lysosomal protective protein, mapped to UniProt P10619. Sequence length is 480 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3913129 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL2171390 | 8.52 | IC50 | 3.0 | Preclinical |
| CHEMBL3947662 | 8.4 | IC50 | 4.0 | Preclinical |
| CHEMBL2171392 | 8.3 | IC50 | 5.0 | Preclinical |
| CHEMBL3900996 | 8.3 | IC50 | 5.0 | Preclinical |
| CHEMBL3959487 | 8.3 | IC50 | 5.0 | Preclinical |
| CHEMBL3945914 | 8.22 | IC50 | 6.0 | Preclinical |
| CHEMBL3975529 | 8.15 | IC50 | 7.0 | Preclinical |
| CHEMBL3944726 | 8.1 | IC50 | 8.0 | Preclinical |
| CHEMBL3977104 | 8.1 | IC50 | 8.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 11 | 754 | 6.1 |
| cell-based format | 2 | 32 | 7.0 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 6 | 0 | — |