Disintegrin and metalloproteinase domain-containing protein 33 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q9BZ11. Use UniProt Q9BZ11 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9BZ11 as the stable identity anchor, then attach disease evidence before program review.
Disintegrin and metalloproteinase domain-containing protein 33
Review this target as Disintegrin and metalloproteinase domain-containing protein 33, mapped to UniProt Q9BZ11. Sequence length is 813 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Disintegrin and metalloproteinase domain-containing protein 33 as ChEMBL target CHEMBL6121, mapped to UniProt Q9BZ11. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Disintegrin and metalloproteinase domain-containing protein 33 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9BZ11 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Disintegrin and metalloproteinase domain-containing protein 33 |
| UniProt Accession | Q9BZ11 |
| Component Type | Protein |
| Sequence Length | 813 aa |
Disintegrin and metalloproteinase domain-containing protein 33
Review this target as Disintegrin and metalloproteinase domain-containing protein 33, mapped to UniProt Q9BZ11. Sequence length is 813 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL148169 | 7.82 | Ki | 15.0 | Preclinical |
| CHEMBL3643916 | 7.62 | IC50 | 24.0 | Preclinical |
| CHEMBL3643914 | 7.58 | IC50 | 26.0 | Preclinical |
| CHEMBL3643913 | 6.83 | IC50 | 147.0 | Preclinical |
| CHEMBL3643908 | 6.74 | IC50 | 181.0 | Preclinical |
| CHEMBL3643910 | 6.74 | IC50 | 181.0 | Preclinical |
| CHEMBL3643911 | 6.6 | IC50 | 249.0 | Preclinical |
| CHEMBL3643909 | 6.53 | IC50 | 298.0 | Preclinical |
| CHEMBL3643912 | 6.48 | IC50 | 328.0 | Preclinical |
| CHEMBL3643915 | 6.33 | IC50 | 469.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 2 | 12 | 6.8 |